DPCstruct | MC4449

Metacluster Properties and Pfam Annotations

Number of structural domains6
Mean domain length (aa)138 ± 11 aa
Standard deviation of domain lengths10.75
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score76.94
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.76
Mean intra-cluster local Distance Difference Test score0.78
Mean intra-cluster sequence similarity (%)54.76
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4U5TV08 4-122 SPPGGCGHVSVLRCFPASVGRDVAVAVVKALGVCLGNPDTQSLLQTDRQVKWTMEVLCYGLTLPLDGDTVKLCVDVYTDWLMALVYQ…
K1QHN2 1-138 MYSEWASLQDEIQCDKANQSVLHKFPTPVGTTVATSVVRHIAVSLSITANSQEPCQLDSDKEVKWAMEVLCYGLGLPLTELDTIKEC…
A0A5E4Q421 1-156 None
A0A3S2P3U8 2-141 None
A0A4C1X798 2-138 None
A0A821QXX8 2-141 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.