DPCstruct | MC44480

Metacluster Properties and Pfam Annotations

Number of structural domains45
Mean domain length (aa)226 ± 42 aa
Standard deviation of domain lengths42.09
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score89.96
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.61
Mean intra-cluster local Distance Difference Test score0.53
Mean intra-cluster sequence similarity (%)19.41
Pfam Score100.00
Assigned Pfam label(s) PF04240

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6J4HWB7 19-246 ALVFLVLMWLAQVATPLFERGQRQAPTTAVVVLLAASALCAAAASVGWWRALVAVTAATAVGFAVEAVGTRTGLPFGEYRYSGALQP…
A0A849IHL5 19-228 PWVLVGVIVWRCFGWRRAVLWLGVGWALAFAAEWSSTSGPGIPFGVYHYHPGGLSHDWTLLGVPLFDSLSFGWLAFCTYAVMGSLGA…
D7CS25 252-471 None
A0A662E566 23-317 None
E3J0A8 95-350 None
A0A3G8YEM1 260-489 None
E8U4M4 75-316 None
A0A044SLY4 11-334 None
A0A2M7UG87 5-202 None
A0A3P3RMV3 30-265 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.