DPCstruct | MC4448

Metacluster Properties and Pfam Annotations

Number of structural domains36
Mean domain length (aa)199 ± 34 aa
Standard deviation of domain lengths34.22
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score65.95
Mean fraction of residues predicted as intrinsically disordered0.45
Mean length-normalized TM-Score0.56
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)27.07
Pfam Score100.00
Assigned Pfam label(s) CL0123

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A834DEP3 1-139 MATPKPRILPWLVSQLDGGHLEGVAWLDPSRTRFRIPWKHGLRQDAQQEDFGIFQAWAEASGAYTPGKDKPDLPTWKRNFRSALNRK…
A0A556V8H2 5-183 GRRLKQWLIEQINSNIYSGLLWEDEVHTMFRIPWKHAGKQDYNQEVDASIFKAWAVFKGKFKEGDKAEPATWKTRLRCALNKSPDFE…
A0A6I9Y9L0 55-198 None
H0YV95 112-300 None
A0A3M0J7F0 132-381 None
S9XQQ4 866-1010 None
A0A7I8VTN2 211-365 None
A0A6J0V6G8 5-205 None
A0A3M6V3K3 3-256 None
A0A7J7KSB4 1-240 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.