DPCstruct | MC44474

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)180 ± 14 aa
Standard deviation of domain lengths13.67
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score88.11
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.86
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)42.37
Pfam Score100.00
Assigned Pfam label(s) CL0126

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7Y2HU99 1-170 AAEADEVFREEMRQRFNEPWRTLLGHMRHESGHYYFGEVVGDSNREAARALFGDETSNYSQALDHYYNNGPLPNWNERFISAYASAH…
M2AYV9 62-233 AEADSVHRERLRVKLGEPQRTLIGHMRHEVGHYIDWAWASRVAPAKYHALFGDPNTLDYGEAMKKHYAVGAPANWADRHVSAYATMH…
A0A258B7B6 2-149 None
A0A2P8KF45 209-399 None
A0A4Q2XTL8 98-275 None
A0A6N2DGU2 291-466 None
A0A0S8EYM3 165-336 None
A0A378UAM5 327-510 None
A0A257XYK3 51-248 None
A0A249P0K5 2-203 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.