DPCstruct | MC44451

Metacluster Properties and Pfam Annotations

Number of structural domains606
Mean domain length (aa)93 ± 15 aa
Standard deviation of domain lengths14.62
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score79.16
Mean fraction of residues predicted as intrinsically disordered0.36
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)21.18
Pfam Score96.07
Assigned Pfam label(s) PF19331- PF15697- PF18140- CL0105- PF02817

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
D7G4Z4 589-661 None
A0A812EVW3 672-755 None
A0A2C6KN14 79-187 None
A0A0R2Q2W6 123-210 None
A0A2W5XF09 82-172 None
A0A1L2FV46 96-229 None
A0A2V6QZ33 3-99 None
Q13085 747-820 None
A0A817I0G1 287-418 None
A0A6N2LRG3 367-463 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.