DPCstruct | MC44451

Metacluster Properties and Pfam Annotations

Number of structural domains606
Mean domain length (aa)93 ± 15 aa
Standard deviation of domain lengths14.62
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score79.16
Mean fraction of residues predicted as intrinsically disordered0.36
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)21.18
Pfam Score96.07
Assigned Pfam label(s) PF19331- PF15697- PF18140- CL0105- PF02817

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A521ST03 160-261 None
A0A4Z2DI64 565-649 None
A0A162AN21 11-100 None
A0A5N6JWV6 1-95 None
A0A1I7VXR0 369-467 None
A0A109W246 485-578 None
S7WTC0 140-222 None
E8N370 40-129 None
L0PD22 1-88 None
A0A6I9XCZ9 344-417 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.