DPCstruct | MC44451

Metacluster Properties and Pfam Annotations

Number of structural domains606
Mean domain length (aa)93 ± 15 aa
Standard deviation of domain lengths14.62
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score79.16
Mean fraction of residues predicted as intrinsically disordered0.36
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)21.18
Pfam Score96.07
Assigned Pfam label(s) PF19331- PF15697- PF18140- CL0105- PF02817

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
J4U7K5 8-111 STSFTSAPVVVEVPQMAESITEGTLKQFNKEVGDFVKADEEIATIETDKIDVSVNAPQSGKILKFLANEDDTVTVGQALVELEPGEA…
A0A1B3SL93 3-80 KVKFKNSRKYKGIVESVLVSDGQPVKAGDLLAKVSTQVEKFEIKSPINGYIRNIYIIESLIVSHGDTLFDVINWRELD
A0A2J8AFC0 21-147 None
A0A1B0BUA5 65-148 None
A0A7S2UBK6 455-539 None
A0A6D2HY35 502-602 None
A0A7S0YMC2 46-167 None
A0A1C3K3F6 132-242 None
A0A7R8X7K2 314-392 None
A0A6V8DAA4 324-399 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.