DPCstruct | MC44448

Metacluster Properties and Pfam Annotations

Number of structural domains34
Mean domain length (aa)161 ± 14 aa
Standard deviation of domain lengths13.91
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score85.11
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)43.64
Pfam Score92.73
Assigned Pfam label(s) PF03460- CL0667

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1W9F6L3 17-178 SKGDIIQAVNKGCHTVAALKAETKAGTGCGGCIPLLTQVLNAELSKQGIEVNHHLCEHFAYSRQELFHLIRVEGIKSFEALLTKYGK…
A0A0B8PBW1 21-166 GDIKQAVASGCTTMAELKETTNASTGCGGCSALAKQVLDSELLSLGVEVNNDLCEHFAYSRQELSDIVRINQIKTFDELLEKYGSGL…
A0A378A120 268-425 None
A0A7Y3J0M4 404-574 None
A0A1F2RU33 2-196 None
A0A0K2RHP0 2-157 None
A0A377DLR7 243-391 None
A0A261XZX7 475-627 None
A0A6I1ISC8 1-155 None
A0A011P3X0 8-185 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.