DPCstruct | MC44424

Metacluster Properties and Pfam Annotations

Number of structural domains38
Mean domain length (aa)195 ± 43 aa
Standard deviation of domain lengths43.30
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score66.46
Mean fraction of residues predicted as intrinsically disordered0.62
Mean length-normalized TM-Score0.34
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)33.68
Pfam Score91.95
Assigned Pfam label(s) PF12253- PF11600- PF15539

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0N5D4M5 247-439 VSLAPHIRRDPLSADVHDNLLQIPPPVCFTLNLKKSKLFQFHDNWRPAYYGTWRKQSHFITGRRPFAKDTMFFDYEVDSDEEWEVPE…
H2ZDV8 2-161 INIRAKLMQFCENNRPPYYGTYRKRSKYIRPRRPFIKDADLLDYEVDSDDEWEDPADGEDIANSDGEEDGDKDEDKEDDEGDGFFVP…
A0A1X2GB98 30-190 None
A0A444XNW4 167-355 None
A0A1X2IGP8 64-258 None
J5RFD0 145-425 None
A0A7S2XVB8 14-158 None
H9G514 337-650 None
A0A1B7MJ05 76-299 None
A0A0D8YAW8 174-371 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.