DPCstruct | MC44405

Metacluster Properties and Pfam Annotations

Number of structural domains62
Mean domain length (aa)180 ± 31 aa
Standard deviation of domain lengths31.07
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score84.78
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.76
Mean intra-cluster local Distance Difference Test score0.78
Mean intra-cluster sequence similarity (%)35.05
Pfam Score88.44
Assigned Pfam label(s) CL0052- CL0036

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
W4QIA8 408-579 GRLLPGKMLLVDLEKKTIVPDEKLKKAYAKKHPYKKWLDQNLIPLHTLSPNSQSEEPITGDELVRLQAAFGYTVEEINKLIKPMVTD…
A0A287HCY2 43-231 ASEVGVIPMDESKVVMKGRLGPGMMITVDLETGQVLENTEVKKNVASAKPYGTWLQESTRSIKPVNFQSSPVMDNETILRHQQAFGY…
A0A0G4KM02 412-595 None
A0A811EBX1 394-577 None
A0A2X2ECS6 166-359 None
A0A1C6I1V6 18-145 None
A0A0B8P763 221-435 None
A0A0Q9XCL6 452-638 None
A0A2R7RNQ8 236-449 None
A0A212DLH0 162-284 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.