DPCstruct | MC44383

Metacluster Properties and Pfam Annotations

Number of structural domains334
Mean domain length (aa)244 ± 76 aa
Standard deviation of domain lengths76.05
Length coefficient of variation0.31
Mean AlphaFold2 pLDDT confidence score77.69
Mean fraction of residues predicted as intrinsically disordered0.39
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.61
Mean intra-cluster sequence similarity (%)20.27
Pfam Score73.40
Assigned Pfam label(s) CL0023- PF01556- CL0123- CL0159- PF00684

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A355AZM0 148-391 IHRAYRRLAFEFHPDRHAGQLEMEARFKEIGEAYRALISGAGEDAPPTLDASDDLSARGRDLHFDIMVDFLEAAAGGEVGVRIQRPF…
K2CFP1 1-137 MTIEFMEAVKGSEKSFVHQGRQYTVKIPPGSDDGTRIRYSEFDVSINVKPHKTFRREGNDVFIYHEIPLTLAILGGETSVPTLEGEL…
F6H935 123-342 None
A0A0C2J3N5 3-146 None
B0EIW1 6-169 None
A0A1B0C165 31-368 None
A0A6D2I0V1 402-745 None
B0EUK2 590-757 None
A0A654HC41 1-163 None
K7F9P6 1-203 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.