DPCstruct | MC44327

Metacluster Properties and Pfam Annotations

Number of structural domains79
Mean domain length (aa)266 ± 52 aa
Standard deviation of domain lengths51.86
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score90.47
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.73
Mean intra-cluster local Distance Difference Test score0.67
Mean intra-cluster sequence similarity (%)32.02
Pfam Score98.48
Assigned Pfam label(s) CL0475- CL0063

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
L8M6N6 178-477 GGLAEEITKGADTLLAMVKDPECKVFLTLSGAMTIAKMGLIICDMVDLGIIDSICSTGALMAHGLVESVGLKHFKYDPNEDDANLAD…
A0A813B0C4 9-233 GGIEEDFMKCFRPHYLGDFELKGSELRMRGINRIGNLLVPNNNYCKFEDWFSPLLHEMHDEQEKYGTVWTPAKMIARMGEAINHEDS…
A0A1P8BA27 10-174 None
A0A838UTN2 217-472 None
A0A524HY82 5-230 None
A0A2H6KDI8 56-369 None
A0A453DTU1 59-315 None
A0A182FFE2 49-357 None
A0A3M1QIJ7 182-402 None
A0A4W6DZN1 20-213 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.