DPCstruct | MC44313

Metacluster Properties and Pfam Annotations

Number of structural domains117
Mean domain length (aa)260 ± 53 aa
Standard deviation of domain lengths52.93
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score90.51
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.60
Mean intra-cluster local Distance Difference Test score0.52
Mean intra-cluster sequence similarity (%)20.52
Pfam Score87.19
Assigned Pfam label(s) CL0722- CL0697- CL0051

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1C6JJT3 169-416 LTDYTMEEFFRFAKETPVEDLYFIREAYRVNLELAKAALTSERCTLTKSLLAFNGGTDVSGDLRATARFFAGAASEARVLGLDKPAM…
A0A376VM99 2-246 RVPGTQFQLDPVQAAFNIGAMIRWLDFNDTWLAAEWGHPSDNLGGILATADWLSRNAVASGKAPLTMKQVLTAMIKAHEIQGCIALE…
V8QVV8 1-249 None
A0A7J2L367 62-303 None
A0A4Q4ZLC0 807-1010 None
A0A2Z2PGS7 4-254 None
A0A560FP59 16-267 None
A0A365MRJ4 3-305 None
A0A2N3S4H6 315-659 None
A0A2N3SJK9 1-207 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.