DPCstruct | MC44310

Metacluster Properties and Pfam Annotations

Number of structural domains257
Mean domain length (aa)224 ± 54 aa
Standard deviation of domain lengths53.68
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score89.00
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.60
Mean intra-cluster local Distance Difference Test score0.52
Mean intra-cluster sequence similarity (%)19.35
Pfam Score99.12
Assigned Pfam label(s) CL0056- CL0364- PF18596

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1Z8LXM0 17-227 DENSPRELPIDPVNIYHTATIEKDGYFESRVDLSGHCSTHIDVPCLMYKNGFTVADIPIEKLFGRSILIDLSENKRPGDAITAEDLQ…
A0A023G4U2 6-175 HFNKHGWSASEIPLDRLLMVPIALIDVQQEAARNASYLMPVAEVLRWEAQNGPLPSNCLLLIRSGWSKYYNNRNAFYGVDQYGIRHI…
A0A2H4S7Y8 311-606 None
A0A3E0CX78 149-370 None
A0A7E5VAR3 14-195 None
A0A6A3AV24 624-837 None
A0A2T0Q1S2 48-314 None
A0A177V0K3 83-433 None
A0A2V6TQH8 1-184 None
A0A1J5L8N9 2-135 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.