DPCstruct | MC44293

Metacluster Properties and Pfam Annotations

Number of structural domains62
Mean domain length (aa)149 ± 31 aa
Standard deviation of domain lengths31.49
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score77.11
Mean fraction of residues predicted as intrinsically disordered0.34
Mean length-normalized TM-Score0.69
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)25.98
Pfam Score97.83
Assigned Pfam label(s) PF10273- PF05056- CL0186

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0G4H905 1-169 MENRDEVFSRAVASVFSNWTLLNLAVDGGWGGRQSRKKCIDLFEEVIDKFRRGERFGADGLADFLFHRIAKLFSTSCEDGSVEEVAA…
A0A0C2CZU7 7-96 SSNEWKSIVCRVIASWGGYQLGVDFSSGGPETLAKDEWFKDVLAEYIFTTRGLKAEDLEDWLNNILYTEFNLILEDDSVYPTSLLLI…
A0A4U0VME3 643-829 None
K8EBP8 90-267 None
A0A7M3RPX8 81-264 None
A0A835HMI3 44-242 None
A0A183J656 2-177 None
A0A369RRC2 5-169 None
A0A2U1M9F4 90-239 None
A0A2K3NPR8 230-399 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.