DPCstruct | MC4426

Metacluster Properties and Pfam Annotations

Number of structural domains133
Mean domain length (aa)266 ± 50 aa
Standard deviation of domain lengths50.06
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score87.61
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.68
Mean intra-cluster local Distance Difference Test score0.67
Mean intra-cluster sequence similarity (%)24.91
Pfam Score97.66
Assigned Pfam label(s) PF16484- CL0149- PF05760

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
F7E6D9 429-725 DSLPPLPVPSLEESLKKYLDSVKPFATNEEYQRTQEIVAKFHRGIGQALHQKLLERAKGKRNWLEEWWLNVAYLDVRIPSQLNVNFA…
A0A3P7H090 28-268 PVRQFYEVVQGGYKCPRCGGREQVGLNTTNTMKHLKARHETEYAELVEALSHRKQPLEQWWYDAYNEIRSPLAPFLSLASVNQRFAP…
D6W820 37-373 None
A0A5J5CBD6 261-574 None
A0A5J5CWP0 23-298 None
A0A1V6TPB7 272-564 None
A0A817PKP6 450-728 None
E7FA20 4-301 None
A0A4Y2U3B2 8-235 None
A0A819TAP7 43-312 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.