DPCstruct | MC44227

Metacluster Properties and Pfam Annotations

Number of structural domains121
Mean domain length (aa)319 ± 78 aa
Standard deviation of domain lengths78.10
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score80.10
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.50
Mean intra-cluster local Distance Difference Test score0.58
Mean intra-cluster sequence similarity (%)22.81
Pfam Score80.53
Assigned Pfam label(s) PF04560- PF04997- CL0410- PF04983- PF00623

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0P7I0W8 8-408 KEIGKISFGLMDPETYRDMSATKVITADTYDDDGYPIDMGLMDPRLGVIDPGLECRTCGQHSGSCNGHFGHIELAAPVIHVGFAKLI…
A0A5S9M380 1-235 MGHIELAAPVSHIWYFKGIPSRMGLVLDMSPRALEEVIYFASYVVTDPGNTPLEKKQLLSEKEFRAYLDKYGNTFQAAMGAEAINKL…
A0A7S0MHA2 4-199 None
A0A4Z2HLZ3 2-386 None
A0A3R6IGC9 67-272 None
A0A834SQQ6 18-341 None
T1GNZ5 4-303 None
A0A5J4VK66 12-367 None
A0A835R4S9 11-333 None
A0A7C6Y895 143-470 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.