DPCstruct | MC44191

Metacluster Properties and Pfam Annotations

Number of structural domains311
Mean domain length (aa)137 ± 26 aa
Standard deviation of domain lengths25.89
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score88.94
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.56
Mean intra-cluster local Distance Difference Test score0.53
Mean intra-cluster sequence similarity (%)19.31
Pfam Score84.16
Assigned Pfam label(s) CL0032- CL0227- CL0202- CL0036

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A243RUU6 5-132 RAVRAAAYCVPTDQPEADGTLVWDATTLVVAEVDAEEIVGTGWAYAPAAAVSFITETLAAVATGADALDIPATWTAMVRQVRNAGRT…
A0A4U9CZ37 21-123 TLIVEVEADSGQTGFAVTTAGEMGCFIVEKHLSRFVEGKCVSDIKLIHDRMLNATLFYSGSGGLVLNTISCIDLALWDLFGKVVGLP…
A0A0V0Q9N7 7-155 None
A0A424L195 38-210 None
A0A2V7YDK0 129-299 None
A0A2V7Y948 211-350 None
A0A7M3RN17 1-133 None
A0A7C1MCZ2 66-226 None
A0A135V828 21-140 None
A0A1A9VKA2 1-165 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.