DPCstruct | MC44135

Metacluster Properties and Pfam Annotations

Number of structural domains1283
Mean domain length (aa)217 ± 43 aa
Standard deviation of domain lengths42.96
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score74.27
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.33
Mean intra-cluster local Distance Difference Test score0.41
Mean intra-cluster sequence similarity (%)13.82
Pfam Score86.77
Assigned Pfam label(s) PF20150- CL0505- CL0020- CL0271- PF09803

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
K2SF12 1-239 None
A0A2H3CZJ8 2-153 None
A0A2H3CXF7 89-332 None
A0A6A5WT61 90-319 None
A0A4U0VJN4 4-151 None
A0A4U0V8Y4 11-175 None
A0A5N6EFX9 8-202 None
A0A6G1IWE6 21-169 None
A0A2V5J172 99-257 None
A0A4V2MWQ1 1-191 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.