DPCstruct | MC44135

Metacluster Properties and Pfam Annotations

Number of structural domains1283
Mean domain length (aa)217 ± 43 aa
Standard deviation of domain lengths42.96
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score74.27
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.33
Mean intra-cluster local Distance Difference Test score0.41
Mean intra-cluster sequence similarity (%)13.82
Pfam Score86.77
Assigned Pfam label(s) PF20150- CL0505- CL0020- CL0271- PF09803

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A178ELL1 10-214 GDTSSESDTLSQSKSEIQQCSPLLDLPAEIRNMIYKYVLGNWTICAFSRTHRPAQYVIVDPFYTWHRNPPTNKLNVLSTCRQIYTEA…
A0A139HIV9 1-177 MAGDRKTTSCLLSLPPEIQLIIWEFTVTSTDPLLINCACDSSYGGWTEEYYADRELWEKGERHPPWQPGLTRACASIRADALKMFYK…
A0A2H3GKR1 3-203 None
A0A2H3G898 2-192 None
A0A4Z0YM01 20-245 None
A0A4Z0YBJ7 29-225 None
A0A1V6SE41 1-176 None
A0A6A5VBN5 20-230 None
A0A6A5V9P2 1-161 None
A0A6A5V1V5 18-199 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.