DPCstruct | MC44116

Metacluster Properties and Pfam Annotations

Number of structural domains297
Mean domain length (aa)376 ± 85 aa
Standard deviation of domain lengths85.46
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score78.65
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.45
Mean intra-cluster local Distance Difference Test score0.46
Mean intra-cluster sequence similarity (%)11.81
Pfam Score23.87
Assigned Pfam label(s) PF04860- PF06381- PF12236- PF06074- PF13264

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A376VJE6 3-258 None
A0A236MRM7 174-630 None
A0A5F2EFT7 70-464 None
A0A0C6F7S6 27-424 None
A0A1V6DRW6 3-333 None
A0A838PEK8 452-728 None
A0A355B6J3 10-297 None
B7JNZ4 2-238 None
A0A377M4B7 3-253 None
A0A3L7MQ77 13-356 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.