DPCstruct | MC44116

Metacluster Properties and Pfam Annotations

Number of structural domains297
Mean domain length (aa)376 ± 85 aa
Standard deviation of domain lengths85.46
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score78.65
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.45
Mean intra-cluster local Distance Difference Test score0.46
Mean intra-cluster sequence similarity (%)11.81
Pfam Score23.87
Assigned Pfam label(s) PF04860- PF06381- PF12236- PF06074- PF13264

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0P6XFV9 14-382 ARRIVELTTQYVVGGGLAVSAKDAAAQQFLKAFWRSRLNRMETRCMEWCDELARSGNLFVLLSTDAAGMSYARAVPAASIQRIETRS…
A0A379FHT7 59-346 AVFYPITGNTRNGMIGMAFKKDPLVAVVEKLSCLKDDADGAGSSIYQLAQSSLESVLEVGRHGLYVDYNSDSKLPYIFQYRAEDIIN…
A0A1G3YGW0 43-441 None
A0A7X7VHG3 7-485 None
A0A2P8EL50 26-517 None
A0A356FYW8 88-523 None
A0A2T2RLK0 52-442 None
A0A497NLK4 44-609 None
A0A2U8G2R7 476-1161 None
A0A7W1C4U2 2-404 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.