DPCstruct | MC4409

Metacluster Properties and Pfam Annotations

Number of structural domains6
Mean domain length (aa)139 ± 11 aa
Standard deviation of domain lengths10.83
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score77.98
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.73
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)30.56
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2R6WWR5 198-337 VVFDTIADRFFSLDFRHLQRVPTSHCWDGGESRLIVCETAQEHLEATSISGKNSGDLQLTVLFATSEDGLLELEQVDIGFKSRLLGM…
M7BY25 189-328 DRIPVSHFWDHSEPRLFVCEAVLEPNLQFPDKKQQQTESSESTPDVLIISFFSTEEHGLLLQDSFPLPSTYQALLGIEVPHYYFAKK…
A0A176WBE2 135-277 None
A0A1D1ULT8 439-558 None
A0A1X7VEQ4 36-168 None
A0A5N4C053 91-246 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.