DPCstruct | MC44024

Metacluster Properties and Pfam Annotations

Number of structural domains61
Mean domain length (aa)213 ± 27 aa
Standard deviation of domain lengths26.83
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score77.25
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.60
Mean intra-cluster local Distance Difference Test score0.56
Mean intra-cluster sequence similarity (%)23.23
Pfam Score98.65
Assigned Pfam label(s) PF19160- CL0016

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A444X3F1 9-223 FGFAVFLGMHFPPLMADCPLDFSASNFTLASSLCSNQGDRGNCCRYINANVAISVARFANSTSILGVPPNDSVSCLQTISDKLQLNG…
A0A072VGE1 6-204 MFLLLLFTLSIATPSASSISCPMDLSYVETFPWDTSSCRDPIDTQHCCQTLLSLFGIGLAKHLKETSLFQLPNKNTLKSCLQDFKLK…
A0A1E5UVL6 19-200 None
A0A835RR05 13-257 None
A0A287IGX0 7-190 None
A0A4D9BK61 8-271 None
A0A446MD58 7-233 None
A0A446MA38 60-271 None
A0A2N9I6Y3 25-240 None
A0A1U8FRZ0 9-212 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.