DPCstruct | MC44021

Metacluster Properties and Pfam Annotations

Number of structural domains60
Mean domain length (aa)79 ± 12 aa
Standard deviation of domain lengths12.17
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score90.39
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.87
Mean intra-cluster local Distance Difference Test score0.82
Mean intra-cluster sequence similarity (%)52.71
Pfam Score98.53
Assigned Pfam label(s) CL0016- CL0036

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A444WZ46 109-175 QEGSYPGGVHLEMTGQNVTECVGGSRTITYDDLSSRYHTHCDPRLNASQSLELAFNIAERLRKKRMQ
X8F731 72-137 RHFDRIVDEVQGFFEVHRGLGTHPGGIHVEITGENVTECLGGAQDISDSDLSGRYETACDPRLNTQ
R9NVV2 427-539 None
A0A2I0HTI0 22-106 None
A0A655JG07 112-183 None
A0A655F824 282-353 None
A0A6A2XM19 325-401 None
L8HFZ7 335-429 None
A0A1V5J5Y8 51-125 None
A0A6A6LCL5 1139-1223 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.