DPCstruct | MC43963

Metacluster Properties and Pfam Annotations

Number of structural domains17
Mean domain length (aa)162 ± 18 aa
Standard deviation of domain lengths17.85
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score83.21
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.71
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)21.87
Pfam Score95.45
Assigned Pfam label(s) PF00118- PF15065

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6I9YVF5 3-169 AAAAAAAPWAGLALLWAAGFCAGDAKGYRRRVSLEYNPGWASSRVNLLHTRAVGLNDTLHYVWSTIGVPTVLLVYTASDSSSLRVNW…
A0A673GBN2 2-155 VSRCLREYLNPGLTPPLVLPQGVGLVHVRGLGQSDTLHFLLCNHGAPALLMVNTYSTQSAVQVDWPAFINRSSSGSLRVEPQTSVRY…
A0A2R7WFT5 122-278 None
A0A2K6KMZ0 31-190 None
A0A4Y2LQR4 16-169 None
A0A6V7HEH1 101-294 None
A0A654GJE7 18-164 None
A0A0X3NR34 1-200 None
A0A095A6T7 142-326 None
A0A2A4JVD7 582-727 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.