DPCstruct | MC43951

Metacluster Properties and Pfam Annotations

Number of structural domains52
Mean domain length (aa)84 ± 22 aa
Standard deviation of domain lengths21.85
Length coefficient of variation0.26
Mean AlphaFold2 pLDDT confidence score67.91
Mean fraction of residues predicted as intrinsically disordered0.38
Mean length-normalized TM-Score0.58
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)35.20
Pfam Score98.84
Assigned Pfam label(s) PF17181- PF13259

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6A6LH87 218-290 NLQQQRKHMVLGSKPPGCVNKCFSCKPCMATLVVPSHQKDPTFKALSHGDDDDSGRYYLLSWKCRCGEKLFQP
A0A5D2Z4R8 74-123 RMMGRLGSRPPNCERKCGGCRPCVATQIPATTDKLGIQYTNYEPEGWKCK
A0A0D2RG96 25-119 None
D8RVS9 76-174 None
A0A426YFG4 3-60 None
A0A6J1GIN2 3-156 None
A0A4P1RR20 10-93 None
A0A811NV78 82-140 None
A0A4Y7J7T1 35-108 None
A0A7N2KNX1 41-121 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.