DPCstruct | MC43941

Metacluster Properties and Pfam Annotations

Number of structural domains27
Mean domain length (aa)82 ± 7 aa
Standard deviation of domain lengths6.68
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score94.74
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.87
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)38.02
Pfam Score100.00
Assigned Pfam label(s) CL0036

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A380KMG3 1-85 MLHLADGGDKSAFQWWLDEITKQSVDFDIVGISYYPYWYGTLAELSENMDNISERYNKKVVVVETAYANTLDNLDQKTNAVTATE
A0A485B3C7 1-85 MLHLAEGTKNDTFRWWFDEISKRNVPYDIIGLSMYTYWNGPISALKANMDDISRRYNKDVIVVEAAYAYTLENCDNAENSFQAKE
E6LHW7 74-155 None
F2JNT0 552-631 None
A0A2X1B5A4 1-84 None
A0A3R5WJ32 401-480 None
A0A5S9MKS3 107-191 None
A0A315XWK6 230-309 None
E4Q4A2 112-194 None
A0A402DQI6 240-321 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.