DPCstruct | MC43893

Metacluster Properties and Pfam Annotations

Number of structural domains100
Mean domain length (aa)80 ± 18 aa
Standard deviation of domain lengths17.75
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score86.39
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)25.87
Pfam Score98.75
Assigned Pfam label(s) PF00327- PF00410

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
O67562 2-56 SKLKVKLLRGLAGESERHIQAVKSLGLKKRGQERILEDNPLVWGNIRKAFHLVGV
A0A821LZ41 12-83 HKLHIVTRIRSTKRRSYWEKDTIKMLGLQKAHSPQIHKNILSVNAKLKVVKHLIRIQPLKLPQGLPTEETMS
R7UJU9 1-106 None
F4PZJ8 59-126 None
A0A0C2J3T8 2-72 None
A0A084RS45 659-738 None
A0A3A4UFF9 2-76 None
A0A6I8NY50 248-342 None
T0TB38 3-82 None
A0A2E4AEA4 45-104 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.