DPCstruct | MC43775

Metacluster Properties and Pfam Annotations

Number of structural domains297
Mean domain length (aa)134 ± 21 aa
Standard deviation of domain lengths21.19
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score82.65
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.58
Mean intra-cluster local Distance Difference Test score0.54
Mean intra-cluster sequence similarity (%)21.76
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A378WNH3 227-366 None
A0A378WNA0 428-564 None
A0A153JGL2 23-154 None
H3RLF2 274-405 None
A0A804UG50 6-131 None
A0A5C5CUS4 48-200 None
A0A7W1B708 416-591 None
H8LMJ0 279-401 None
A0A2D0LEJ6 9-159 None
A0A7U6A7M5 39-158 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.