DPCstruct | MC43775

Metacluster Properties and Pfam Annotations

Number of structural domains297
Mean domain length (aa)134 ± 21 aa
Standard deviation of domain lengths21.19
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score82.65
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.58
Mean intra-cluster local Distance Difference Test score0.54
Mean intra-cluster sequence similarity (%)21.76
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4R3YSG8 40-179 NPGPRQTRYLSPLERDDQQISFLSGCVHWMNRPFARPSDGLAPGDYIYVITVDGNFLAIEQQPTDMREVHHSTIPSGKGLICAGHMT…
A0A4Q7XZA6 6-130 QARVYPNLNPSAAVPVDRDQIFSLSSFADNYRMRRGKEHGQYVPNARFTFVKLTSGETLMHQRFRHPVLAEGRPVLYAGEAYFNNGK…
A0A3D1QUY4 20-151 None
A0A2M8WW33 432-557 None
A0A3N7G2J1 77-213 None
Q3YS63 98-235 None
A0A5E4EJE1 59-171 None
A0A3G7UCB2 109-246 None
A0A268AG62 400-512 None
A0A7Y6YZX7 481-614 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.