DPCstruct | MC43747

Metacluster Properties and Pfam Annotations

Number of structural domains78
Mean domain length (aa)136 ± 20 aa
Standard deviation of domain lengths20.32
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score71.52
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)30.37
Pfam Score98.36
Assigned Pfam label(s) CL0369- PF04825- CL0221

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4W4E0X6 2-127 VFFTELFSYKRGSLAKIWLAAHWEKKITKAHVFECNLETTVEDIISPQIKIGLRTSGHLLLGVARIYSRKTKYLLADCSDAVVKIKV…
A0A5S6QIA0 1-141 MFYSLNILARKDGKFSIVWLAATRANKLSKKQCQAVDLCYSCIELCKHIPSSNRVKGAERFSLYLCSQLMFGIVVIFGKKHEYLLRE…
A0A2P4YM93 185-298 None
A0A7N0TQH9 1-142 None
A0A146H5X4 3-165 None
A0A6P5F437 1-132 None
J4UGW4 393-525 None
A0A6I9YF37 1-128 None
A0A446JDW5 2-153 None
A0A4Z1HAV6 2-133 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.