DPCstruct | MC4374

Metacluster Properties and Pfam Annotations

Number of structural domains14
Mean domain length (aa)75 ± 5 aa
Standard deviation of domain lengths5.01
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score83.51
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.77
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)22.95
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1G4AJI9 1-74 MMIEAIREFKRAVPFRPYEIRTNGGERLRVPHPDFILVAPKGSWVMVTDEKDHPRHISALLIEEVAPLRKRTRK
A0A517R7A6 19-95 EPIKFTQKIHRLLRARPFRSFRLYLSDGSEFEVRHPESALLTQGGLYIGRYADEQSEIPESDAFCSLLHMTRVEVDE
A0A7C4UXC5 5-74 None
A0A2E8D149 15-92 None
A0A517XPF0 4-84 None
A0A2V5QAC1 1-77 None
A0A3A0C9P0 3-82 None
A0A2V5R8Z4 5-71 None
A0A7C4UPN9 1-64 None
A0A1G1BV11 175-249 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.