DPCstruct | MC43733

Metacluster Properties and Pfam Annotations

Number of structural domains16
Mean domain length (aa)122 ± 27 aa
Standard deviation of domain lengths26.56
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score91.95
Mean fraction of residues predicted as intrinsically disordered0.34
Mean length-normalized TM-Score0.87
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)37.57
Pfam Score100.00
Assigned Pfam label(s) CL0257

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5F2B033 10-121 KKNAMSLNISNLFACVRPNQKENFPFESMEEYLERKRPDGFSEDPWVRVHEKAGGKRIRIEERSMYVSGSVEQWETWTQMKFPESGS…
A0A5F1XYD0 68-179 KKNAMSLNISNLFACVRPNRKENFPFISMEEYLERKRPDGFSEDPWVRVHEKAGGKKIRIEPRSMYVSGSVEEWETWTRMKFPESGS…
A0A5C8ZEF5 135-246 None
A0A2T6ZAI0 279-420 None
A0A1U9ZZB2 39-149 None
A0A7C8Q3V4 1-208 None
A0A1H9M1G9 316-429 None
A0A257RFR9 111-222 None
A0A7W5W040 3-113 None
V5FXW2 144-289 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.