DPCstruct | MC43720

Metacluster Properties and Pfam Annotations

Number of structural domains35
Mean domain length (aa)62 ± 7 aa
Standard deviation of domain lengths6.99
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score77.32
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.82
Mean intra-cluster local Distance Difference Test score0.86
Mean intra-cluster sequence similarity (%)58.00
Pfam Score100.00
Assigned Pfam label(s) CL0408

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5C6SXP9 49-98 MESAGLWEDLPCVVVKGVCDYADSHKNKEWQNFAAATSASVVKALLERYI
A0A168CA88 1-60 MEAAGVMTCILVGVIRGVCDYGDEHKNKQWQPYAAAVAAAYAKAVLARIPPKVAVRVEGQ
A0A101MAL1 34-89 None
A0A4Z0Y5X3 23-84 None
A0A0D2H9B2 1-73 None
A0A084RZL2 1-57 None
A0A3D8RYI5 21-75 None
A0A5N5WVE4 1-51 None
A0A4S9IUA6 83-146 None
A0A4Q7K4V1 100-164 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.