DPCstruct | MC437

Metacluster Properties and Pfam Annotations

Number of structural domains16
Mean domain length (aa)76 ± 6 aa
Standard deviation of domain lengths5.66
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score80.73
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.77
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)36.48
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A049DXT9 50-126 ERYLNSGLLPVDCRFCHARVAVRRLGPGHTAVQWNTEAWQRCAYFTEVRQAGGDTARTKSCPKLGDSIEHAVAEGYL
A0A543BZ50 10-94 DLPMTPVECQRCHATVQVRKSSWQQTSVQWDEAGARTCPERRPSLIAGGIREADFFTCAGLRESIAQAAMSGTIPMAEETFEDSA
A0A2A3GCV3 1-72 None
A0A6I6G3J8 33-113 None
A0A7I7K117 6-83 None
A0A1A3J7D2 71-146 None
A0A1I5J4K4 32-104 None
A0A1X1B1Y1 33-107 None
A0A6B2RSM0 1-64 None
A0A2A3FHT7 1-80 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.