DPCstruct | MC43666

Metacluster Properties and Pfam Annotations

Number of structural domains2571
Mean domain length (aa)142 ± 27 aa
Standard deviation of domain lengths27.30
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score79.48
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.58
Mean intra-cluster local Distance Difference Test score0.53
Mean intra-cluster sequence similarity (%)17.10
Pfam Score95.81
Assigned Pfam label(s) CL0213- PF00057- CL0022- CL0144- CL0202

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4U5MEQ1 22-197 None
A0A0G4NH24 545-701 None
A0A4U5LVA7 248-387 None
A0A4U5LXR0 22-166 None
A0A4U5LXT8 105-292 None
A0A4U5M2I7 321-536 None
A0A4U5M4B3 111-242 None
A0A4U5M4E1 158-307 None
A0A4U5M4C1 169-300 None
A0A4U5LQK1 263-389 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.