DPCstruct | MC43666

Metacluster Properties and Pfam Annotations

Number of structural domains2571
Mean domain length (aa)142 ± 27 aa
Standard deviation of domain lengths27.30
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score79.48
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.58
Mean intra-cluster local Distance Difference Test score0.53
Mean intra-cluster sequence similarity (%)17.10
Pfam Score95.81
Assigned Pfam label(s) CL0213- PF00057- CL0022- CL0144- CL0202

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
W5M587 90-226 None
A0A7E4W8J1 101-268 None
W6JJB5 200-351 None
A0A0K0EG95 5-138 None
A0A1I8I3R1 233-373 None
A0A1I8IFB7 363-596 None
A0A1I8IJ31 19-183 None
A0A1I8IME4 71-243 None
P21755 38-142 None
A0A7E4ZR95 112-244 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.