DPCstruct | MC43666

Metacluster Properties and Pfam Annotations

Number of structural domains2571
Mean domain length (aa)142 ± 27 aa
Standard deviation of domain lengths27.30
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score79.48
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.58
Mean intra-cluster local Distance Difference Test score0.53
Mean intra-cluster sequence similarity (%)17.10
Pfam Score95.81
Assigned Pfam label(s) CL0213- PF00057- CL0022- CL0144- CL0202

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6A5HH50 13-247 None
A0A6A5HUN9 127-307 None
A0A4E9F2N6 84-268 None
A0A2I0LIT6 149-239 None
A0A2I0M0A3 40-189 None
A0A016X2Q9 175-290 None
E4XAI6 190-337 None
A0A0D6L652 17-140 None
E4WQ91 2-144 None
E4WT25 13-114 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.