DPCstruct | MC43666

Metacluster Properties and Pfam Annotations

Number of structural domains2571
Mean domain length (aa)142 ± 27 aa
Standard deviation of domain lengths27.30
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score79.48
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.58
Mean intra-cluster local Distance Difference Test score0.53
Mean intra-cluster sequence similarity (%)17.10
Pfam Score95.81
Assigned Pfam label(s) CL0213- PF00057- CL0022- CL0144- CL0202

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7E4SEI1 123-262 None
A0A3B5A4G7 22-144 None
A0A498MIM3 21-136 None
A0A6A4VGW8 62-263 None
A0A6A4VFA8 222-348 None
A0A6A4VED6 650-820 None
A0A7R9VFE4 9-166 None
Q2H296 31-145 None
A0A2R9B5K8 43-184 None
R9KLK4 244-390 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.