DPCstruct | MC43666

Metacluster Properties and Pfam Annotations

Number of structural domains2571
Mean domain length (aa)142 ± 27 aa
Standard deviation of domain lengths27.30
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score79.48
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.58
Mean intra-cluster local Distance Difference Test score0.53
Mean intra-cluster sequence similarity (%)17.10
Pfam Score95.81
Assigned Pfam label(s) CL0213- PF00057- CL0022- CL0144- CL0202

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3S1A3H8 20-165 LVLASQNPCRFGWAYFQGSCYGFGHERMTWPEAEQMCVLYEGTLAEIHSKAENDFVKQYLRNNTILINIYGAWIGGTDIFTEGTWEW…
A0A1I7YPV4 222-359 CPSGFHYFKSFGKCVGAFDIAGRKPKNPSQMKKLCTDLKSLPVKIENKQQNDDLNHIDTWNVALIGLHIPEGQPWGKNNYRWISDDS…
A0A2B4SGK4 1006-1141 None
A0A2B4SJS4 643-786 None
A0A2B4SLL8 205-345 None
A0A1D2N6J6 1-151 None
A0A1H5S9P9 649-788 None
A0A819T2R6 499-675 None
A0A7M3RK12 2-222 None
A0A7M3RQH8 420-595 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.