DPCstruct | MC43642

Metacluster Properties and Pfam Annotations

Number of structural domains18
Mean domain length (aa)108 ± 18 aa
Standard deviation of domain lengths18.33
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score66.41
Mean fraction of residues predicted as intrinsically disordered0.80
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.78
Mean intra-cluster sequence similarity (%)36.94
Pfam Score100.00
Assigned Pfam label(s) CL0214

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A022QU39 10-107 EYCREPGRNAAGETGRNAAGETAATADNMGLDMLMNMFRGLGTVGGMTTPNSSQAPPEELYATQLSQLREMGFIDTQENIRALIAAA…
A0A093YNQ0 1-76 MGGGEGGGANPYAGFGAAGAGGATSPPPPADTRPPEEVYADQLRALNDMGFFDFEANVRALRRSGGSVQGAVEQLL
A0A7S3AIJ9 127-256 None
D4ATJ4 542-619 None
A0A7S0L6U0 7-113 None
W7TEA5 16-124 None
A0A448ZPD4 5-138 None
U6JSD1 129-223 None
A0A6A5X2W4 213-294 None
A0A6A5U2C4 8-98 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.