DPCstruct | MC43634

Metacluster Properties and Pfam Annotations

Number of structural domains178
Mean domain length (aa)124 ± 24 aa
Standard deviation of domain lengths24.43
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score87.65
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.61
Mean intra-cluster local Distance Difference Test score0.58
Mean intra-cluster sequence similarity (%)20.19
Pfam Score43.92
Assigned Pfam label(s) CL0169- PF14319- CL0481- CL0023

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A848A1T3 2-114 LLPVPYFLVTFTVPEPLRLWMRSHPDVSLDLLFAASAHALQDLARNPQRLGASLGMLGLLHTWSRTLIYHPHVHYLVPAGGLSLDQR…
A0A4U2DCN5 89-196 VHYFMVTFTLPYQLRVLARHQPKAIYNGMFKVASGVLKDFANRQRQGELGFTAVLHTHSRQRNLHPHLHIIVAAGQYDASRQTWHKG…
A0A846MBJ1 9-170 None
A0A100I159 196-351 None
W3YLP4 53-153 None
A0A1Q8YGR4 16-121 None
A0A7V8YDI4 105-222 None
A6MV72 258-393 None
A0A3R8J2E8 101-232 None
A0A348XIG8 7-121 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.