DPCstruct | MC43624

Metacluster Properties and Pfam Annotations

Number of structural domains19
Mean domain length (aa)153 ± 32 aa
Standard deviation of domain lengths32.06
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score86.55
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.55
Mean intra-cluster sequence similarity (%)17.79
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7X2S7S0 26-177 SFIIEKAAKLGIRHDLVEYQNHYESSYNEFEAWLSDLLQQKKPPADLEALCFSLYETAETVTMFIAGAEEWDEEGDWALAKDYAPLS…
A0A2U2HM43 1-107 MPKTVVAYSFNLFELPPGDAKYGIELIGADEFDTDNSDWACSEIWVANPRSISIPRAFADGAWEGCLDDVRGLLTSTLSTSSATASK…
A0A518B2D7 5-203 None
A0A495KQD8 99-255 None
A0A2S8HA09 15-147 None
A0A3B8I1U9 18-182 None
S6ET75 28-197 None
A0A1H5YZD8 1-122 None
A0A238U8G6 149-286 None
A0A1M3HM43 13-147 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.