DPCstruct | MC43613

Metacluster Properties and Pfam Annotations

Number of structural domains11
Mean domain length (aa)66 ± 5 aa
Standard deviation of domain lengths4.72
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score81.17
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.79
Mean intra-cluster local Distance Difference Test score0.90
Mean intra-cluster sequence similarity (%)60.58
Pfam Score100.00
Assigned Pfam label(s) CL0208

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
M1D605 35-99 EDLSTKAKSRFSVSLRSLSQPMSLKDIAKTWDVCARAVICEYAQQSGGGTFSSKYGSWENCSTAA
A0A7N2KPP8 1-76 MVHLLNWLEDHEDLSVKVKSRLKVSLRSLLKPWSLGEIAMTWDFCVRAVISEHAQQNGGGNFSLKFGTWENFLSVA
A0A2N9GK05 768-834 None
A0A453RSV0 1-67 None
A0A6J1CCM7 296-357 None
A0A2P2MQK9 216-275 None
A0A5N5FUD2 803-865 None
A0A6P8BS42 56-129 None
A0A7J6VEH8 88-154 None
A0A1D6KLU1 461-527 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.