DPCstruct | MC4359

Metacluster Properties and Pfam Annotations

Number of structural domains28
Mean domain length (aa)108 ± 14 aa
Standard deviation of domain lengths13.65
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score73.88
Mean fraction of residues predicted as intrinsically disordered0.54
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.83
Mean intra-cluster sequence similarity (%)56.51
Pfam Score85.21
Assigned Pfam label(s) PF16835- CL0361

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7S2XJI1 286-385 TDRQNRVGSKFGGGGVSSGQNSERDRKERLRELALESVDLAKDPYLMRNHLGTYECKLCLTLHTNEGNYLAHTQGKKHQSGLAKRAL…
A0A1I8JA33 1-108 MDFQHRPGGKTGTGGVASWSDSNRDRRERLRQLALETIDLQKDPYFMKNHLGTYECKLCLTLHNNEGSYLAHTQGKKHQQNLARRAA…
A0A067CJZ5 1-104 None
A0A218WRP5 3-108 None
A0A177SZA4 1-141 None
A0A7R9L7M8 1-108 None
A0A1L0G9G2 1-126 None
A0A820ZCT3 3-111 None
A0A401S4E3 3-111 None
A0A7S2EFW9 138-269 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.