DPCstruct | MC4357

Metacluster Properties and Pfam Annotations

Number of structural domains190
Mean domain length (aa)264 ± 53 aa
Standard deviation of domain lengths53.34
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score83.56
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)29.93
Pfam Score77.50
Assigned Pfam label(s) PF04560- PF21091- PF04997- PF04998- PF00177

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4U5Q422 125-461 None
A0A2H4FMB0 775-1104 None
A0A2W4KB56 99-379 None
D0EVW4 144-440 None
A0A811R5L9 13-223 None
U6KTH3 115-434 None
A0A820REV5 74-346 None
A0A820AGP6 101-420 None
A0A2P0QH24 316-639 None
A0A7R8HB64 268-592 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.