DPCstruct | MC4357

Metacluster Properties and Pfam Annotations

Number of structural domains190
Mean domain length (aa)264 ± 53 aa
Standard deviation of domain lengths53.34
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score83.56
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)29.93
Pfam Score77.50
Assigned Pfam label(s) PF04560- PF21091- PF04997- PF04998- PF00177

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A832X431 1-181 ISINEVGVPDFVASELTVPEKVTAHNLEEMKTIVRNGPNTHPGANYVIRNDGRRKKITDTTKDDVAEELDVGFTVERQLRDGDIVLF…
A0A7J8D1L4 257-550 PLSVRPAVVMQGSARNQDDLTHKLADIVKINNQLRRNEQNGAAAHVIAEDVKLLQFHVATMVDNELPGLPRAMQKSGRPLKSLKQRL…
A0A4Y7L9T1 141-427 None
A0A1A9X8V1 11-252 None
A0A5S6Q651 207-523 None
A0A7C6Y895 361-687 None
A0A7S0MHA2 82-388 None
A0A446JE33 2-197 None
A0A4Z2HLZ3 252-582 None
P14248 277-572 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.