DPCstruct | MC43543

Metacluster Properties and Pfam Annotations

Number of structural domains15
Mean domain length (aa)112 ± 9 aa
Standard deviation of domain lengths8.62
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score88.52
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.92
Mean intra-cluster local Distance Difference Test score0.88
Mean intra-cluster sequence similarity (%)69.04
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A453E6T8 1-108 GNGLAGGGGGRVSINVFSRHDDTQIFVHGGMSSGCPDNAGAAGTLYDAVPKSLDVNNNNMSTQTDTLLLDFPNQPLWTNVNIRNHAK…
A0A287F010 271-385 GGSIYLKAATMQGGGKISACGGNGLSGGGGGRVSIDVFSRHDDTHFFVHGGRSSGCPGNAGAAGTLYEEVPKSITVSNNNLSTQTDT…
A0A446IQS4 6-105 None
A0A453A9X6 1-89 None
A0A287KCP5 135-253 None
A0A1D6LZX3 275-389 None
A0A453E6Z4 192-310 None
A0A397Z4N3 221-336 None
A0A804UFJ3 269-387 None
A0A287F021 2-102 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.