DPCstruct | MC43532

Metacluster Properties and Pfam Annotations

Number of structural domains61
Mean domain length (aa)112 ± 17 aa
Standard deviation of domain lengths17.41
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score74.29
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)26.76
Pfam Score91.79
Assigned Pfam label(s) PF20451- PF20452

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A453DTS6 12-115 MMGDGMTDRMWEVTTSHARTCDAGDKVYAYAGQHGATVYVNSLCQLVRLEFAGVECAAQQLTRAQKAYVHQLYVEAFEQRHSLQEVE…
A0A287QPK7 207-297 MSPAAWKAIIEHAMTCKVGDTLYMHEIKESNMEFFFDAILQLVGVKFGDCYKPLDMIHPAEKNLVETLKQKAYENMKDVQYDHIMIN…
A0A2G3ATF8 135-247 None
Q852B6 50-152 None
A0A5P1ESP7 529-653 None
A0A287QP84 242-380 None
A0A7J8LR12 6-120 None
A0A835ENT3 359-447 None
A0A022RS14 224-363 None
A0A2T7F7Z1 190-292 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.